Kidney and Metabolic Bone Diseases Vol.32 No.1(3)

Theme Uremia and bone
Title Bone mass and morphology in dialysis patients
Publish Date 2019/01
Author Keiichi Sumida Division of Nephrology, Department of Medicine, University of Tennessee Health Science Center
[ Summary ] Dual-energy X-ray absorptiometry (DXA) is the standard method of measuring bone mass, or bone mineral density (BMD), in patients with end-stage renal disease on dialysis. However, it is technically impossible to use BMD to assess bone quality, which is often altered in dialysis patients. Recent advances in radiological techniques, such as high resolution peripheral quantitative CT (HRpQCT) and trabecular bone score (TBS), have enabled us to noninvasively evaluate bone microstructures, the efficacy of which has been proven in clinical studies. We hope that the widespread availability of these emerging tools will lead to new innovative discoveries both in bone morphological analysis and in fracture risk prediction among patients receiving dialysis and ultimately contribute to improved outcomes.
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