| Theme | Pediatric bone : From fetus to adolescent | |
|---|---|---|
| Title | Vitamin D-related bone diseases in children | |
| Publish Date | 2015/07 | |
| Author | Sachiko Kitanaka | Department of Pediatrics, Graduate School of Medicine, the University of Tokyo |
| [ Summary ] | Humans obtain vitamin D either by diet or by sunlight exposure. Vitamin D is converted to its active form after going through two hydroxylation steps. A deficiency of vitamin D action in children or infants results in rickets and hypocalcemia. The main causes of vitamin D related rickets are vitamin D deficiency and congenital diseases of vitamin D dependency. This review summarizes the etiology, diagnosis, and management of these vitamin D-related diseases. | |