Kidney and Metabolic Bone Diseases Vol.28 No.3(10)

Series Case Report
Title A case of unexplained hypercalcemia with varied clinical manifestations
Publish Date 2015/07
Author Ryota Yasukawa Department of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
Author Junichiro James Kazama Department of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
Author Ichiei Narita Department of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
Author Emiko Kouno Department of Nephrology, Nagaoka Chuo General Hospital
Author Yohei Tsuchida Department of Nephrology, Nagaoka Chuo General Hospital
Author Takuma Takada Department of Nephrology, Nagaoka Chuo General Hospital
[ Summary ] A 66-year-old woman with lumbar spinal compression fracture presented with transient hypercalcemia. She was referred to our hospital due to a relapse of hypercalcemia. Based on her laboratory data, adrenal insufficiency was considered to have caused the hypercalcemia. Her serum calcium levels gradually decreased and remained within the physiological range from 6 months after the condition first developed. Moreover, anemia, eosinophilia, and elevated serum alkaline phosphatase levels were also temporarily noted. The administration of alendronate could have been a possible, but unlikely, cause of these symptoms. If the patient was indeed suffering from adrenal insufficiency temporarily, the sequence of symptoms can be explained in an integrated manner. However, we failed to determine the final diagnosis in the current case.
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