| Theme | Chronic kidney disease and aging -- Phosphate connection | |
|---|---|---|
| Title | Physiological roles of osteocytes : Analysis of osteocyte–ablated mice | |
| Publish Date | 2015/01 | |
| Author | Sawako Tatsumi | Department of Molecular Nutrition, Institution of Health Biosciences, The University of Tokushima Graduate School |
| Author | Osamu Fujii | Department of Molecular Nutrition, Institution of Health Biosciences, The University of Tokushima Graduate School |
| Author | Haruna Sakaguchi | Department of Molecular Nutrition, Institution of Health Biosciences, The University of Tokushima Graduate School |
| Author | Mao Ogata | Department of Molecular Nutrition, Institution of Health Biosciences, The University of Tokushima Graduate School |
| Author | Tomohiro Arakaki | Department of Molecular Nutrition, Institution of Health Biosciences, The University of Tokushima Graduate School |
| Author | Kenichi Miyamoto | Department of Molecular Nutrition, Institution of Health Biosciences, The University of Tokushima Graduate School |
| [ Summary ] | Osteocytes are terminal differentiated cells derived from osteoblasts. Osteocytes are buried in the bone matrix, and communicate with each other as well as with cells on the bone surface, including osteoblasts and osteoclasts. Recently, osteocytes have been reported to participate not only in bone metabolism, but also in inorganic phosphate metabolism and fat metabolism. This review summarizes the physiological role of osteocytes, including the observation and analysis of osteocyte-ablated mice. | |