Kidney and Metabolic Bone Diseases Vol.25 No.4(5)

Theme Clinical practice guideline for CKD-MBD
Title Management of CKD-MBD during predialysis period
Publish Date 2012/10
Author Hirotaka Komaba Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine
[ Summary ] Chronic kidney disease-mineral and bone disorder (CKD-MBD) develops early in the course of CKD and should be recognized as a progressive disorder beginning in the predialysis period. Recent epidemiologic data has demonstrated that the association between abnormalities in biochemical parameters of CKD-MBD and mortality and poor renal outcomes can be found in predialysis patients, suggesting that interventions during the predialysis period to control biochemical parameters improve patient-level outcomes. Under these circumstances, the Japanese Society for Dialysis Therapy released "Clinical Practice Guideline for CKD-MBD" in March 2012. It is hoped that this new guideline not only improves management of CKD-MBD in predialysis patients in Japan but also becomes a good chance to produce evidence for predialysis CKD-MBD from Japan.
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