| [ Summary ] |
Several key enzymes associated with the glycolytic cycle contain magnesium as cofactors, which are magnesiumdependent enzymes. Significantly negative correlations exist between serum magnesium levels and FBS, HbA1c, fructosamin and fasting insulin levels in diabetic patients. After long-term diabetic states (10-15 years), diabetic nephropathy can occur, indicating first proteinuria andthen decrement of kidney function. A man with diabetic nephropathy was examined in this study. In elderly inpatients with less than 60 ml/min/1.73 m2 of eGFR, FBS increase when serum Mg levels decrease for two periods for a means of 6.1 months in the same subjects, indicating the benifi ts of high serum magnesium levels on lowering FBS. |