| [ Summary ] |
Inflammatory bowel disease (IBD) is associated with a high incidence of bone loss : reported prevalence rates range from 20 to 60%. The mechanism of bone loss in IBD is associated with multiple pathophysiological factors, such as malabsorption, vitamin D deficiency, loss of body mass index, small bowel resection, hypogonadism, chronic inflammatory process, and corticosteroid use. Although the high incidence of bone loss, the overall fracture risk for IBD patients is not largely increased, with an overall fracture risk of 1.41 compared with control groups. The epidemiology of osteoporotic fractures associated with IBD as well as evidence-based rational prevention strategies and therapeutic strategies, remain unresolved. It is generally agreed that there is a need to increase awareness of inflammatory bowel disease-associated osteoporosis. Further research should focus on the identification of high fracture risk patients with IBD. |