Kidney and Metabolic Bone Diseases Vol.17 No.3(5)

Theme Evidence-based strategies for secondary hyperparathyroidism
Title The management for vascular calcification in end stage renal failure patients
Publish Date 2004/07
Author Keitaro Yokoyama Department of Nephrology and Hypertension, Jikei University School of Medicine
[ Summary ] Coronary artery calcification, observed in most ESRD patients beyond their 20s, has been reported to influence mortality and complications of cardiovascular diseases in end stage renal failure patients. On the other hand, we have been able to use the new phosphate binder, sevelamer which dose not contain calcium and will able to use calcimimetics for secondary hyperparathyroidism soon. Thus, we should evaluate bone diseases as well as cardiovascular diseases according to changes in the paradigms for renal osteodystrophy. Undoubtely imaging methods play a major role on the management of complications in end stage renal failure patients. Multidetector-row CT (MDCT) is a most useful imaging method, having high temporal resolution and high spatial resolution. We were able to obtain adequate image quality for diagnosis and evaluation in 26 cases (87%), except for 4 cases not evaluated due to severe calcification. Therefore, this study suggested that 16-row MDCT is useful as a screening test for CAG even in dialysis patients.
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