| [ Summary ] |
Osteoporosis has been defined as a disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to enhanced bone fragility and a consequent increase in risk of fracture. However, the relationship between bone mass and trabecular microarchitecture to bone strength has not been fully established. In the present study, we examine the relationship between bone mass and trabecular microarchitecture to bone strength of lumbar vertebra after ovariectomy in rats. In results, the changes in trabecular bone contour are critical for reducing lumbar bone strength within 4 weeks post-ovx. On the other hand, bone mass was significantly influenced to bone strength from 6 weeks post-ovx. |