The Japanese Journal of Clinical Dialysis Vol.35 No.9(4)

Theme Reconsideration of standard hemodialysis: What is the optimal prescription and management for each patient?
Title Evaluation method of dialysis dose
Publish Date 2019/08
Author Takahiro Shinzato Daiko Medical Engineering Research lnstitute
[ Summary ] Inspite of the fact that Kt/V for urea is a useful marker and predicts survival rates in hemodialysis patients, urea is considered biologically inert. This may indicate that dialysis doses of some other toxic uremic substances vary with Kt/V for urea.
Currently, no dosing parameters have been proposed for protein-bound substances. Nevertheless, considering kinetics of protein-bound substances, the following parameters are important: Kt/V and duration of dialysis session.
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