The Japanese Journal of Clinical Dialysis Vol.35 No.8(15)

Theme Available clinical guidelines for patients on dialysis
Title Contrast-induced nephropathy
Publish Date 2019/07
Author Yoshitaka Isaka Division of Nephrology, Osaka University Graduate School of Medicine
[ Summary ] According to the guidelines on the use of iodine contrast agent in patients with chronic kidney disease, the diagnostic criteria for contrast-induced nephropathy (CIN) is based on the conventional "increase in serum creatinine (SCr) level by more than 0.5 mg/dL or 25 % increase from the previous SCr level within 72 hours." In dialysis patients with abolished kidney function, the condition of CIN is not applicable, but the administration of contrast agents to peritoneal dialysis patients may be a risk factor for residual renal function reduction. Renal replacement therapy (RRT), after the administration of contrast agent, aimed to prevent the onset of CIN does not reduce the risk of developing CIN and RRT is not recommended. Particularly, it is recommended not to force patients for hemodialysis. RRT should be started promptly when CIN induces a possible fatal change in the body fluid volume, electrolytes, and acid-base equilibrium
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