The Japanese Journal of Clinical Dialysis Vol.35 No.6(2)

Theme Evidence and issue for clinical practice of acute kidney injury
Title Epidemiology and risk factors for AKI
Publish Date 2019/06
Author Keisuke Sako Division of Nephrology, Kanazawa University Hospital
Author Kengo Furuichi Division of Nephrology, Kanazawa Medical University Hospital
Author Takashi Wada Division of Nephrology, Kanazawa University Hospital
[ Summary ] In recent years, the incidence of acute kidney injury (AKI) has been increasing. AKI is important not only as a risk factor for chronic kidney disease and end-stage kidney disease but also as a life prognostic factor. Since 2004, RIFLE classification, AKIN classification, and KDIGO classification have been proposed as diagnostic criteria of AKI sequentially. Thereafter, many reports about AKI were published. In 2016, "The Japanese Clinical Practice Guideline for acute kidney injury 2016", which is the first Japanese AKI guideline, was published. The guideline showed that hospital-acquired AKI and community-acquired AKI are dif ferent. Through epidemiological research and multilateral collaborative research, the 0by25 initiative*, has started. Prevention and countermeasures of AKI including those in developing countries are regarded as important. Recently, new risk factors such as recurrent AKI have been reported and follow-up after AKI is also an important subject.

* The 0by25 initiative is an ambitious goal launched by the International Society of Nephrology (ISN) which aims to eliminate preventable deaths from AKI worldwide by 2025.
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