| Theme | Current topics in medical engineering technologies for dialysis therapy | |
|---|---|---|
| Title | Clinical adaptation and efficacy of intermittent infusion hemodiafiltration | |
| Publish Date | 2019/05 | |
| Author | Daigo Kamei | Department of Clinical Engineering, Tokyo Women's Medical University |
| Author | Michio Mineshima | Department of Clinical Engineering, Tokyo Women's Medical University |
| Author | Ken Tsuchiya | Department of Blood Purification, Tokyo Women's Medical University |
| [ Summary ] | Intermittent infusion hemodiafiltration (I-HDF) is a technique used to intermittently infuse ultra-pure dialysates into a patient's blood via a dialysis membrane. I-HDF was developed as a form of online HDF therapy. Several types of dialysis machines (including those employing an I-HDF mode) are commercially available. Presently, I-HDF can be safely and conveniently performed using these machines. I-HDF prevents membrane fouling, improves peripheral circulation, enhances plasma refilling, minimizes the decline in membrane performance that occurs over time, ensures enhanced solute removal, stabilizes blood pressure, reduces the number of required treatments involving medical professionals, particularly in elderly and malnourished patients, in patients with relatively large fluctuations in blood pressure readings, as well as in those with peripheral arterial disease. It is expected that clinical studies performed in the near future will provide a better understanding of the clinical adaptation of I-HDF. |
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