| Theme | Pediatric end-stage kidney disease -- management of transition | |
|---|---|---|
| Title | Acute kidney injury in children and long-term prognosis | |
| Publish Date | 2018/08 | |
| Author | Koichi Kamei | Division of Nephrology and Rheumatology, National Center for Child Health and Development |
| [ Summary ] | KDIGO Clinical Practice Guidelines are recommended for the diagnosis of acute kidney injury (AKI) in children. Serum creatinine levels determined by an enzymatic method should be evaluated using the standard value in Japanese children. A nonrenal disease is the cause of AKI in many children, and the proportion of children with renal disease who received renal replacement therapy for AKI in Japan was 33.5 %. Survival rate of children who received renal replacement therapy for AKI was 54.1 %. Children with AKI due to a renal disease showed better prognosis with respect to survival, despite poor renal prognosis. On the contrary, children with AKI due to a nonrenal disease showed better prognosis in terms of kidney function, despite poor survival-related prognosis. | |