| Theme | Online hemodiafiltration (HDF) -- expansion and issues | |
|---|---|---|
| Title | Clinical efficacy of intermittent infusion hemodiafiltration (I-HDF) | |
| Publish Date | 2017/05 | |
| Author | Kei Eguchi | Department of Clinical Engineering, Tokyo Women's Medical University |
| Author | Michio Mineshima | Department of Clinical Engineering, Tokyo Women's Medical University |
| [ Summary ] | Recently, intermittent infusion hemodiafiltration (I-HDF), in which ultra-pure dialysates are intermittently infused into patients' blood via a dialysis membrane, has been developed as one form of online HDF therapy. Presently, many types of dialysis machines including those employing an I-HDF mode are commercially available. As a result, it has become possible to perform I-HDF treatments using these machines safely and conveniently. As has already been reported, I-HDF is effective in improving peripheral circulation, enhanced plasma refilling, suppression of decreases in membrane performance over time, enhanced solute removal, stabilization of blood pressure, reduction of number of treatments by medical staffs, especially for patients with malnutrition, elderly patients, patients with relatively large blood pressure fluctuation and patients with peripheral arterial disease (PAD). It is expected that the clinical effectiveness of I-HDF will be clarified based on several clinical studies and I-HDF will be further developed in the near future. |
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