The Japanese Journal of Clinical Dialysis Vol.33 No.5(3-3)

Theme Online hemodiafiltration (HDF) -- expansion and issues
Title Safe and effective HDF treatment techniques
Publish Date 2017/05
Author Masahiro Taoka Kaikoukai Medical Foundation Meiko Kyoritsu Clinic
[ Summary ] Online HDF modalities, which can improve solute removal performance as blood purifiers and can perform mass filtration, can provide superior treatment for removing high molecular weight toxins. These therapies help prevent lower extremity irritated feeling, bone and joint pain, pruritus, dialysis amyloidosis, and dialysis hypotension. To improve treatment α1-microglobulin (α1-MG) removal rates must be improved. However, raising removal rates of α1-MG may induce unexpected albumin leakage. Creating safe treatment conditions is required when considerating characteristics of HDF filters.
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