| Theme | Online hemodiafiltration (HDF) -- expansion and issues | |
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| Title | Characteristics of the hemodiafilter | |
| Publish Date | 2017/05 | |
| Author | Michio Mineshima | Department of Clinical Engineering, Tokyo Women's Medical University |
| [ Summary ] | The number of dialysis patients receiving HDF therapy is increasing yearly. In this paper, the characteristics of various types of hemodiafilters are examined. In comparison to dialyzers with high-flux membranes, higher ultrafiltration coefficients are required for hemodiafilters which do not increase albumin loss, especially when employing a post-dilution method. The clinical performance of hemodiafilters usually decreases with time by membrane fouling due to plasma protein plugging of membranes. Specifications for hemodialyzers with low L/(nD), where L, D and n provide effective length, inner diameters and the number of hollow fibers, seem to be suitable to reduce membrane fouling in hemodiafilters. |
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