The Japanese Journal of Clinical Dialysis Vol.32 No.5(2-4)

Theme Recent evaluation and characteristics for dialysis membranes from biocompatible viewpoints
Title Evaluation of dialysis membrane surface structures and surface-protein interactions
Publish Date 2016/05
Author Kenichiro Yamamoto Department of Clinical Engineering, Tokyo Women's Medical University
Author Koki Namekawa Department of Medical Engineering, Junshin Gakuen University
Author Michio Mineshima Department of Clinical Engineering, Tokyo Women's Medical University
[ Summary ] Examination of the relationship between membrane surface structures and protein affinity is necessary to evaluate biocompatibility. Recently, material surface analysis technology operating at nanoscale level has significantly improved. As a result, it has been revealed that uniform surfaces determined with conventional methods are incorrect when determined with nanoscale evaluation. It is possible that nanoscale irregularities may affect the biocompatibility of membranes. Nanoscale control is important to design and develop dialysis membranes which will deliver high performance and high functionality.
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