The Japanese Journal of Clinical Dialysis Vol.31 No.4(4-2)

Theme Death-dealing arrhythmia -- diagnosis, treatment and prevention
Title Electrolyte abnormalities in patients with renal failure
Publish Date 2015/04
Author Takeshi Ideguchi Department of Internal Medicine, Division of Circulatory and Body Fluid Regulation, Faculty of Medicine, University of Miyazaki
Author Tetsunori Ishikawa Department of Internal Medicine, Division of Circulatory and Body Fluid Regulation, Faculty of Medicine, University of Miyazaki
Author Shouichi Fujimoto Department of Hemovascular Medicine and Artificial Organs, Faculty of Medicine, University of Miyazaki
[ Summary ] Patients with renal failure have a risk of electrolyte abnormalities. Thus, prediction and treatment of electrolyte abnormalities are necessary. Before fatal events occur, electrolyte abnormalities should be identified from early symptoms and abnormal ECG findings.
Cardiomyocyte depolarization and repolarization depend on intracellular and extracellular shifts in ion gradients. Abnormal serum electrolyte levels can have profound effects on cardiac conduction and the ECG findings. These may be limited to clinically insignificant changes in 12-lead ECG findings. Bedside ECG can often provide immediate insight and prompt life-saving care. We will review the major ECG findings associated with abnormalities of the major ionic contributors to cardiac conduction, namely potassium, magnesium, and calcium.
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