The Japanese Journal of Clinical Dialysis Vol.31 No.4(2-3)

Theme Death-dealing arrhythmia -- diagnosis, treatment and prevention
Title Long QT-interval and Brugada syndromes
Publish Date 2015/04
Author Nobuhiko Joki Division of Nephrology, Toho University Ohashi Medical Center
Author Shun Kubo Division of Nephrology, Toho University Ohashi Medical Center
[ Summary ] Chronic dialysis is well known to have a great impact on sudden cardiac death. Fluctuant K, Ca, or pH, and sympathetic nerve over-activity are thought to play an important role in the onset of fatal arrhythmic events such as ventricular tachycardia and fibrillation, and consequently, sudden death. Recently, two specific arrhythmic syndromes, namely the long QT-interval and Brugada syndromes, have been noted as causes of sudden cardiac death in the general population. Herein, we provide an overview of the association of the syndromes with sudden cardiac death in dialysis patients.
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