The Japanese Journal of Clinical Dialysis Vol.31 No.1(3)

Theme Early detection and prevention for cancer of dialysis patients
Title Benefits of cancer screening for kidney transplant recipients
Publish Date 2015/01
Author Taigo Kato Department of Urology, Osaka University Graduate School of Medicine
Author Yoichi Kakuta Department of Urology, Osaka University Graduate School of Medicine
Author Toyofumi Abe Department of Urology, Osaka University Graduate School of Medicine
Author Ryoichi Imamura Department of Urology, Osaka University Graduate School of Medicine
Author Norio Nonomura Department of Urology, Osaka University Graduate School of Medicine
Author Naotsugu Ichimaru Advanced Technology for Transplantation, Osaka University Graduate School of Medicine
Author Shiro Takahara Advanced Technology for Transplantation, Osaka University Graduate School of Medicine
[ Summary ] Advances in immunosuppressive agents have significantly improved graft survival in relation to kidney transplantation. Despite these encouraging trends, long-term survival after kidney transplantation has remained unchanged. The high mortality rates in kidney transplant patients are attributed primarily to malignancy as well as infection. The overall risk of post-transplant malignancy (PTM) is considerably higher than in the general population because there are unique points of risk seen in relation to PTM. To improve long-term graft survival rates, clinical physicians should understand the risk factors and pay attention to the incidence of PTM. Cancer screening is a remarkable tool because it provides the advantages of reducing the rate of PTM development and lowering mortality rates associated with kidney transplantation.
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