| Theme | The initiation and maintenance of dialysis in terms of original kidney diseases and complications | |
|---|---|---|
| Title | Polycystic kidney disease | |
| Publish Date | 2014/08 | |
| Author | Tatsuya Suwabe | Nephrology Center, Toranomon Hospital |
| Author | Yoshifumi Ubara | Nephrology Center, Toranomon Hospital |
| [ Summary ] | Autosomal dominant polycystic kidney disease (ADPKD) is a very common renal disorder. Generally speaking, renal cysts in ADPKD patints continue to enlarge from their thirties to their fifties. Approximately half advance to renal failure by 60 years of age. These renal cysts continue to enlarge even after initiation of dialysis. Some patients advance to have marked abdominal distention. Hepatic cysts are aother frequent complication associated with ADPKD. Dialysis patients with conditions caused by ADPKD account for 3.4 % of all dialysis patients in Japan and average age at initial dialysis is 62.5 years. Renal transcatheter arterial embolization (TAE) may be effective for reducing enlarged kidney volume. Compared to renal TAE, the effectiveness of hepatic TAE for reducing liver volume is limited. Cyst induced infections are a frequent and serious complication associated with ADPKD and are often refractory. Cerebral aneurythms are one fatal complication connected with ADPKD, so regular brain MRAs are important. | |