Theme |
Updates on hemodialysis technologies |
Title |
Real time monitoring of solute concentration in spent dialysates |
Publish Date |
2014/05 |
Author |
Ken-ichiro Yamamoto |
Department of Clinical Engineering, Tokyo Women's Medical University |
Author |
Michio Mineshima |
Department of Clinical Engineering, Tokyo Women's Medical University |
[ Summary ] |
The standard evaluation for dialysis dosage is performing by collecting pre- and post-dialysis blood samples. These are analyzed for blood urea nitrogen (BUN) concentrations. However, it is difficult to collect blood samples during all treatments. Continuously monitoring blood levels during treatment is almost impossible because of difficulties with blood sampling. However, it is possible to continuously measure solute concentrations in spent dialysates and to compare equivalent information in the blood. The ability to do this would allow us to quantify Kt/V doses during dialysis treatment and identify patients who are not receiving adequate dosages and to avoid accidents affecting dialysis efficiency. Real time monitoring of solute concentration in spent dialysate fluids may become an essential technique for blood purification. |