| [ Summary ] |
Hypo-responsiveness to ESA (erythropoiesis stimulating agents) is a situation in which patients have been administered sufficient levels of ESA, but their anemia has not improved. This is caused, in many cases, by a wide range of concomitant anemic disorders, including iron deficiency. Additionally, it can also be caused by dialysis treatment for chronic renal failure. Hypo-responsiveness to ESA can have a severe impact on the life expectancy of patients with chronic kidney failure. Hypo-responsiveness to ESA can be caused by a range of factors. However, it is possible to treat cases related to renal failure or dialysis treatment. Therefore, it is vital that these causes not be overlooked. Furthermore, it is possible to minimize anemia by implementing high-quality dialysis therapy, thereby facilitating a reduction in the quantity of ESA. |