| Theme | Current trends and issues for medical management of acute kidney injury in Japan | |
|---|---|---|
| Title | Biomarkers and treatments for acute kidney injury induced by infections/sepsis | |
| Publish Date | 2013/10 | |
| Author | Hideo Yasuda | First Department of Medicine, Hamamatsu University School of Medicine |
| [ Summary ] | Acute kidney injury (AKI) with infection or sepsis has unfavorable outcomes. Prevention and early detection followed by interventions must be provided emergently. The use of novel urinary biomarkers such as liver-type fatty acid-binding proteins (L-FABP) has been developed for early detection and prognosis of AKI induced by sepsis. Resuscitation in intensive care units is based on early goal-directed therapy, leading to prevention of AKI. The avoidance of volume overload and proper intervention through renal replacement therapy have the potential to improve the prognoses for patients suffering from AKI induced by sepsis. | |