| Theme | Current trends and issues for medical management of acute kidney injury in Japan | |
|---|---|---|
| Title | Definition and staging of AKI | |
| Publish Date | 2013/10 | |
| Author | Kazu Hamada | Department of Endocrinology, Metabolism and Nephrology, Kochi University School of Medicine |
| Author | Tatsuki Matsumoto | Department of Endocrinology, Metabolism and Nephrology, Kochi University School of Medicine |
| Author | Taro Horino | Department of Endocrinology, Metabolism and Nephrology, Kochi University School of Medicine |
| Author | Yoshio Terada | Department of Endocrinology, Metabolism and Nephrology, Kochi University School of Medicine |
| [ Summary ] | In March 2012, the outlines known as : KDIGO (Kidney Disease : Improving Global Outcomes) revised the definition of AKI (acute kidney injury) and created the AKI guidelines which summarized RIFLE (Risk, Injury, Failure, Loss, End-stage kidney disease) and AKIN (Acute Kidney Injury Network) classifications. The pivotal points of this guideline are described as the follows : AKI is defined as an increase of more than 0.3 mg/dL in serum creatinine (Cr) levels within 48 hours, the same as the AKIN classification. Furthermore this definition included an increase of more than 1.5 times in serum Cr within 7 days of RIFLE classification. The history of the definition of AKI and the modified KDIGO guidelines are outlined. | |