| Theme | Trend in Peritoneal Dialysis Therapy After Implementation of Japanese Society for Dialysis Therapy (JSDT) Peritoneal Dialysis Guideline | |
|---|---|---|
| Title | The combined therapy with peritoneal dialysis and hemodialysis | |
| Publish Date | 2012/05 | |
| Author | Yukio Maruyama | Division of Kidney and Hypertension, The Jikei University School of Medicine |
| Author | Keitaro Yokoyama | Division of Kidney and Hypertension, The Jikei University School of Medicine |
| [ Summary ] | Peritoneal dialysis (PD) is recommended as a firstline renal replacement therapy (RRT) for end-stage renal disease (ESRD). The factors to support this notion include the fact that residual renal function (RRF), a potent predictor of patient sur vival, is better preserved, as well as an absence of disequilibrium symptoms, and provision of a high quality of life (QOL) for PD patients as compared to patients receiving hemodialysis (HD). However, PD alone is not always successful in correcting inadequate dialysis and/or overhydration after the loss of RRF. Additionally, it is widely recognized that peritoneal membranes gradually deteriorate over the duration of PD therapy. As a result, the efficiency of dialysis cannot be maintained. Combined therapy with PD and HD is a treatment option for PD patients who cannot control inadequate dialysis and/or overhydration after the loss of RRF. In Japan, 20 % of all PD patients are estimated to be on this therapy. We established the Evaluation on the Adequacy of Renal Replacement Therapy (EARTH) Study Group, and demonstrated the clinical utility of this modality in a retrospective multicenter study. |
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