| [ Summary ] |
According to the new classification of CKD by KDIGO, stage 3 CKD should be divided into 3a (eGFR 45-59 mL/min/1.73 m2) and 3b (eGFR 30-44 mL/min/1.73 m2) categories. Among the screened subjects (N=332,174, age 40 to 74 years) enrolled in the Specific Health Check Program (known as the Tokutei-Kenshin), the prevalence of low eGFR, <60 mL/min/1.73 m2, was 14.5 %. The prevalence of dipstick positive (1+ and over) proteinuria was 3.8 %. Compared to US health check subjects Japanese subjects were found to have a distribution of lower levels of eGFR. Exact mechanisms responsible for these differences are not clear but the prevalence of obesity, protein intake and birth weight, which determine the levels of GFR, are obviously different. |