| Theme | Oral Diseases and Oral Care in Dialysis Patients | |
|---|---|---|
| Title | Relationship between renal function and periodontal disease | |
| Publish Date | 2011/06 | |
| Author | Akihiro Yoshihara | Division of Preventive Dentistry, Niigata University Graduate School of Medical and Dental Sciences |
| Author | Hideo Miyazaki | Division of Preventive Dentistry, Niigata University Graduate School of Medical and Dental Sciences |
| [ Summary ] | Osteoporosis is the most common metabolic bone disease observed in elderly patients. Chronic renal failure is associated with marked disturbances in bone structure and metabolism. While some systemic factors which contribute to loss of bone mass and progression of periodontal disease have been identified, we hypothesize that renal function is associated with bone metabolism, and as a result is also associated with periodontal disease. In the present report, we review the relationship between bone metabolism and periodontal disease. Renal function was taken into consideration, in a study of elderly Japanese subjects in Niigata. We evaluated the relationship between bone turnover, renal function and periodontal disease to clarify the disease mechanisms which may be related to each other. A three year longitudinal study clearly demonstrated that systemic loss of bone mineral density is a risk factor for periodontal disease progression. Osteoporosis and low renal function contribute to loss of bone mass. Some systemic factors related to bone remodeling also modify local tissue response to periodontal disease. Systemic bone metabolism, which may be affected by low renal function, is associated with periodontal disease. |
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