| Theme | Prospects for Hemodiafiltration | |
|---|---|---|
| Title | Choosing pre-dilution or post-dilution HDF for chronic dialysis patients | |
| Publish Date | 2011/05 | |
| Author | Shiho Esashi | Yabuki Shima Clinic |
| Author | Ikuto Masakane | Yabuki Shima Clinic |
| [ Summary ] | There are two main dilution methods for hemodiafiltration (HDF) ; pre-dilution and post-dilution. These two methods exhibit different characteristics in terms of removal of uremic substances and clinical advantages. In Japan, HDF is officially recognized for treating dialysis amyloidosis syndrome and intradialytic hypotension, when those conditions are not adequately treated with hemodialysis. Furthermore, bottle or bag type post-dilution HDF is chiefly performed for these indications, because they have been officially recognized for treatment through the medical reimbersment system. Since April 2010, on-line HDF has been covered by medical insurance. As a result, we can provide pre-dilution HDF, which requires a great deal of substitution fluid, for more dialysis patients. We should understand the differences between dilution methods in terms of solute removal and clinical advantages and then choose proper treatment options for individual dialysis patients. |
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