| Theme | New Perspectives of Molecular Biomarker in Dialysis Therapy | |
|---|---|---|
| Title | Biomarker of SLE nephritis and ANCA associated vasculitis | |
| Publish Date | 2011/04 | |
| Author | Wako Yumura | Department of Nephrology, Jichi Medical University |
| Author | Yoshitomo Hamano | Department of Nephrology, Jichi Medical University |
| [ Summary ] | In recent years, the number of patients initially receiving dialysis and those having kidney disease who are senior citizens, has gradually increased. The number of people receiving dialysis due to SLE nephritis does not seem to have decreased. Control of diseases related to SLE is required after dialysis introduction. Diseases leading to multiple organ failure as well as kidney dysfunction may be recognized by examining biomarkers and other clinical indications which are important in indicating the presence of recurring diseases quickly and providing life time maintenance therapy. ANCA associated vasculitis specifically indicates elevated ANCA in many recurrent cases. We must recognize recurrent disease conditions when delivering hemodialysis. Cases exhibiting active signs and changes in serum complement (CH50) titres must be treated appropriately. | |