| Theme | Performance Evaluations for Blood Purification Devices and Characteristics of Dialysis Adequacy Indices | |
|---|---|---|
| Title | Characteristics of indices for hemodialysis adequacy | |
| Publish Date | 2010/04 | |
| Author | Takahiro Shinzato | Daiko Medical Engineering Research Institute |
| [ Summary ] | The most common Kt/V formula corresponds to the variable volume/one-compartment model, and the urea reduction rates used widely today to formulate constant volume/one-compartment models. Adequate doses employing Kt/V may be over 1.2, and an adequate level for urea reduction rates may be over 65 %. TACBUN is obtained by dividing time-averaged urea generation rates by time-averaged urea clearance rates. In other words, TACBUN is determined by two factors (i.e., nPCR and Kt/V). Hence, the impact of TACBUN on risk of death may vary depending on the combination of these two factors. If so, it may not be possible to determine an adequate TACBUN level. |
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