| Theme | Performance Evaluations for Blood Purification Devices and Characteristics of Dialysis Adequacy Indices | |
|---|---|---|
| Title | Compartment models | |
| Publish Date | 2010/04 | |
| Author | Masamiki Miwa | Atsuta Clinic |
| [ Summary ] | When Gotch devised the first Kt/V, he used constant volume/1-compartment models. Thereafter, by analyzing variable volume/1-compartment model, the Shinzato and Daugirdas research groups devised equations by which a single-pool Kt/V may be calculated. The equation to calculate the percentage of creatinine generation rates was also obtained by analyzing this model. Daugirdas determined post-rebound serum urea concentrations by analyzing regional blood flow models and applied these serum urea concentrations to the variable volume/1-compartment model. They determined the equation for equilibrated Kt/V. This Kt/V value is well suited for comparison of dialysis dosage worldwide. |
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