| Theme | How Can We Realize the Philosophy of Chronic Kidney Disease-Mineral and Bone Disorder? | |
|---|---|---|
| Title | Recent progress in calcium and phosphate metabolism control | |
| Publish Date | 2010/01 | |
| Author | Ken-ichi Miyamoto | Department of Molecular Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School |
| Author | Ichiro Kaneko | Department of Molecular Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School |
| Author | Junya Furutani | Department of Molecular Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School |
| Author | Shinsuke Kido | Department of Molecular Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School |
| [ Summary ] | The regulation of calcium and phosphate levels is controlled by the actions of key ions and hormones in the intestines, kidneys, parathyroid gland and bone tissue. The identification of TRPV 5/6, Na/Pi cotransporters, fibroblast growth factor 23 and Klotho have further advanced our understanding of calcium and phosphate homeostasis. This article briefly summarizes how FGF23/Klotho is involved in calcium and phosphate regulation. | |