| Theme | Preventive Medical Screening and Health Check-ups for Dialysis patients | |
|---|---|---|
| Title | Role of residual renal function（RRF）in dialysis patients | |
| Publish Date | 2009/02 | |
| Author | Hidetomo Nakamoto | Department of General Internal Medicine, Saitama Medical University |
| [ Summary ] | RRF (residual renal function) is defined as normal renal functioning possible after induction of maintenance dialysis therapy. The term RRF is used to refer to estimated GFR (glomerular filtration rate), measured as the average of Ccr (creatinine clearance) and Cun (urea nitrogen clearance) based on a 24-hour urine collection schedule. Urine volume over a 24-hour peroid of 100ml or less is considered to represent negligible RRF. Preserving RRF has always been the primary clinical goal for all nephrologists who are managing patients with CKD (chronic kidney disease). In addition, there is clear evidence that preserving RRF remains important after the introduction of maintenance dialysis therapy. RRF plays an important role in maintaining the health and well being of dialysis patients. It not only provides small solute clearance but also plays an important role in maintaining fluid balance, calcium-phosphate control and removal of middle molecular uremic toxins. Maintaining good RRF is the most important benefit of CAPD (continuous ambulatory peritoneal dialysis) in patients with CKD stage 5D. | |