The Japanese Journal of Clinical Dialysis Vol.25 No.1(1-4)

Theme Controlling Infections in Dialysis Patients
Title Systemic fungal infections
Publish Date 2009/01
Author Koichi Izumikawa Department of Molecular Microbiology and Immunology (2nd Department of Internal Medicine), Nagasaki University Graduate School of Biomedical Sciences
Author Shigeru Kohno Department of Molecular Microbiology and Immunology (2nd Department of Internal Medicine), Nagasaki University Graduate School of Biomedical Sciences
[ Summary ] Renal failure, including uremic state is one of the major risk factors of systemic fungal infections (SFIs). The prognosis for SFIs in patients with dialytic treatment is extremely poor. Catheters used for dialysis are important as causes of SFIs, and candidiasis is the most frequent fungal infection. Candida albicans was a major isolate in SFIs, however, the isolation of C. glabrata, also known as azole-low sensitive Candida has been, increasing recently. These trends are affecting the treatment strategy of candidiasis. Appropriate treatment based on rapid and accurate diagnosis is essential for better outcomes.
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