| Theme | New Insights into Uremic Conditions and Their Therapeutic Targets | |
|---|---|---|
| Title | Fundamental pathophysiology of patients with dialysis therapy | |
| Publish Date | 2008/08 | |
| Author | Suguru Yamamoto | Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Science |
| Author | Ichiei Narita | Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Science |
| Author | Fumitake Gejyo | Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Science |
| [ Summary ] | Uremia in hemodialysis patients is related to various types of general disorders, such as anemia, secondary hyperparathyroidism, and dialysis-related amyloidosis. Recently, some systemic disorders, such as chronic kidney disease-mineral and bone disorders (CKD-MBD), cardio-renal anemia (CRA) syndrome, malnutrition-inflammation-atherosclerosis (MIA) syndrome have been suggested as causative factors in dialysis patients having more cardiovascular events and worse prognoses than other patients. Establishing more effective disease preventative measures and dialysis therapy techniques will improve not only mortality rates but also overall quality of life for patients in the future. | |