The Japanese Journal of Clinical Dialysis Vol.24 No.2(1-5-3)

Theme Present Status of Peritoneal Dialysis in Japan
Title Low calcium dialysate and high calcium dialysate
Publish Date 2008/02
Author Hiroyasu Yamamoto Division of Kidney and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine
Author Jun Mitome Division of Kidney and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine
[ Summary ] Peritoneal dialysate calcium (Ca) concentrations are important in strategies for chronic kidney disease-mineral and bone disorder, because the dialysate calcium concentration influences serum calcium levels directly, and may change the dosage of phosphate binders and vitamin-D analogs. High Ca dialysates have been used to correct hypocalcemia in chronic renal failure. Low Ca dialysates were then produced to increase the dosage of Ca containing phosphate binders and vitamin-D analogs. However, there is not enough evidence to choose low Ca dialysates for peritoneal dialysis. When low Ca dialysates are employed it should be recognized that there is a risk of deteriorating secondary hyperparathyroidism.
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