| Theme | The Front of Dialysate Purification Technologies in Hemodialysis Therapy | |
|---|---|---|
| Title | New strategy to control biofilm formation using heated water disinfection | |
| Publish Date | 2007/05 | |
| Author | Kenzo Matsuo | Department of Internal Medicine, Yahata Clinic |
| Author | Reiko Matsuyama | Department of Clinical Engineering,Yahata Clinic |
| Author | Masahiko Nakamoto | Tagawa Municipal Hospital |
| [ Summary ] | Microbial control strategies have been primarily employed using chemical agents in central dialysate delivery systems. However, chemical disinfection is not sufficient to control biofilm formation in dead legs, which is associated with resistance to chemical agents. In order to compensate for the lack of microbicidal effectiveness by chemical germicides in dead legs, heated water disinfection is a novel strategy for clinical hemodialysis systems. Heat can definitely reach each dead leg and disinfect it directly by directing a stream of water at the solid walls, of the systems. Convective heat transfer produces disinfection. Furthermore, heated water disinfection does not lead to residual toxicity as with chemical disinfectants. Therefore, a combination of chemical and thermal disinfection to reinforce the control of microbiological contamination in hemodialysis systems is proposed. |
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