| [ Summary ] |
There have been many reports on the clinical impact of ultrapure dialysis fluids in the retardation of dialysis related amyloidosis and MIA syndrome, for the preservation of residual renal functions and improvements in renal anemia. The common mechanism of these effects is based on the interaction between the retention of uremic toxins and the bio-incompatibility of dialysis therapy alone. There are few reports with high evidence level in these papers. However, our experiences with the purification of dialysis fluids has had a strong impact on our institution and have become a great motivation to keep dialysis fluids clean. Because we have to treat many CKD patients with RRT for long periods in Japan, we must have highly stringent guidelines for dialysis fluid quality. |