The Japanese Journal of Clinical Dialysis Vol.23 No.10(2-1)

Theme Issues of Evidence-based Adequate Dialysis Therapy
Title Adequate peritoneal dialysis and evidence : Dialysis dose
Publish Date 2007/09
Author Noritomo Itami Kidney Center, Nikko Memorial Hospital
Author Masahiro Uemura Kidney Center, Nikko Memorial Hospital
[ Summary ] The 1997 DOQI guidelines for adequate dose of CAPD recommended a combined residual renal and peritoneal dialysis weekly level of Kt/V urea of 2.0 and a weekly Ccr level of 60 l / 1.73 m2. Later, a large scale prospective study, conducted in Mexico and Hong Kong, showed that there was no difference in survival rates with a weekly Kt/V urea level of 2.0 or greater or a weekly Kt/V urea level of 1.7 or greater. Recently, there have been many guidelines formulated which express the minimum dialysis goal as a weekly Kt/V urea level of 1.7.
In Japan, where there are a large number of patients receiving long-term peritoneal dialysis, the adequacy of the dialysis doses noted above should be analyzed taking into consideration race and body structure. The dialysis doses and background circumstances concerning current guidelines for various countries are outlined.
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