| Theme | Intractable Infection in Hemodialysis Patients -- Current Diagnosis and Treatment | |
|---|---|---|
| Title | Multi-drug resistant Pseudomonas aeruginosa and Enterococci | |
| Publish Date | 2006/02 | |
| Author | Kazunori Tomono | Infection Control Team, School of Medicine, Osaka University |
| [ Summary ] | Mulin-drug resistant organisms tend to spread in healthcare settings, and the treatment for multi-drug resistant bacterial infections is prevention. The recommendations for preventing transmission of infectious agents in healthcare settings are the standard precautions, surveillance, judicious antimicrobial use and decontamination of medical equipment. As Pseudomonas aeruginosa and Enterococci are virulent organisms that are susceptible to only a limited number of antibiotic agents, infections caused by this organism are difficult to cure and often require combination therapy. The increasing resistance of P. aeruginosa and Enteroccoci are growing threats to the clinical management of health care associated infections. Prompt and intensive chemotherapy is recommended for hemodialysis patients, because their conditions will become more serious when treatment for infection is delayed. To achieve effective antimicrobial chemotherapy, it is necessary to use information from drug susceptibility tests and therapeutic drug monitoung (TDM). |
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