The Japanese Journal of Clinical Dialysis Vol.22 No.10(2-8)

Theme Dialysis Re-initiation and Related Cares after Functional Loss of Transplanted Kidney
Title Clinical and social problems in kidney retransplantation
Publish Date 2006/09
Author Ken Morita Urological Surgery, Hokkaido University Hospital
Author Yoshihiko Watarai Urological Surgery, Hokkaido University Hospital
Author Katsuya Nonomura Urological Surgery, Hokkaido University Hospital
[ Summary ] We reviewed the clinical course of 2 kidney retransplant cases out of 87 kidney recipients who underwent kidney transplantation in our institute over the past ten years. Six of 87 patients lost allograft functions during this period, we summarized and discussed the clinical history and social backgrounds of these recipients. In order to be successful candidates for retransplantation, patients need new live kidney donor candidates, priority on cadaveric kidney waiting lists, especially for pediatric recipients, good control of post-transplant infectious diseases and negative anti-HLA antibody production.
Graft and patient survival rates for kidney retransplantation are inferior to those for primary kidney transplantation. We must minimize the co-morbidity related to dialysis therapy, post-transplant immunosuppression, risk of recurrent kidney disease, retrieval of primary kidney allografts and post-transplant infectious disease. Social problems inherent in recipient's families should be seriously considered if the retransplant donor candidate is a living relative.
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