| Theme | Malignant Tumors in Patients with End-Stage Renal Failures | |
|---|---|---|
| Title | Increased prevalence of malignancy in uremic patients on chronic dialysis in Kyushu-Okinawa area | |
| Publish Date | 2005/04 | |
| Author | Kazo Kaizu | Department of Nephrology & Blood Purification, Social Insurance Yokohama Central Hospital |
| [ Summary ] | This study was designed to clarify the incidence of malignant tumor in dialysis patients in the Kyushu-Okinawa area. This questionnaire study covered 71.0 % (23,042 patients) of all chronic dialysis patients (32,468 patients as of 31st, Dec, 2002). There were 980 patients with 1,046 MT (single : 917 pts, double : 60 pts, triple : 3 pts). The largest number of patients with MT was in those where it was observed in the digestive organs. 481 patients had MT of the digestive tract, 257 patients had MT of the urinary tract, 80 patients had MT of the breast, followed by 59 in respiratory system. Standardized incidence rates (SIR) adjusted for sex and age, using cancer incidence rates from the cancer registry in Japan was as follows (M / F) : total 3.0 / 3.3, kidney 17.6 / 22.5, thyroid 10.0 / 5.6, multiple myeloma 6.3 / 12.5, bladder 10.0 / 5.6 and liver 5.8 / 4.7, although this is not accurate because of cross-sectional study. 51.7 % of dialysis patients were diagnosed with MT within four years after initiation of dialysis. Conclusion : The risk of MT for dialysis patients may increase compared to population controls. The MTs of the kidney, liver, colon, bladder, thyroid and multiple myeloma showed higher incidence rates in dialysis patients than in control populations. |
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