| Theme | Trace Elements in Dialysis Treatment | |
|---|---|---|
| Title | Protective effects of zinc on development of bone disease in patients with chronic renal failure | |
| Publish Date | 2004/08 | |
| Author | Masanori Shibata | Department of Clinical Engineering, Taigenkai Hospital |
| Author | Etsuko Yamaga | Department of Clinical Engineering, Taigenkai Hospital |
| Author | Kojiro Nagai | Department of Nephrology, Kyoto University |
| Author | Shinkichi Taniguchi | Department of Internal Medicine, Taigenkai Hospital |
| Author | Kazumasa Usami | Department of Internal Medicine, Taigenkai Hospital |
| Author | Shiro Kawashima | Tonokosei Hospital |
| [ Summary ] | An adequate intake of zinc has a protective effect on the development of renal osteodystrophy and/or secondary hyperparathyroidism in patients with chronic renal failure, treated with maintenance hemodialysis according to detailed dietary analysis. Serum levels of parathyroid hormone were significantly lowered by oral administration of polaprezinc, a zinc-containing compound to treat peptic ulcers, in patients with secondary hyperparathyroidism. The roles of zinc in bone metabolism in patients with chronic renal failure, and the possible therapeutic effects of this metal in the treatment of such complications were also discussed, including special reference to recently clarified evience about the functions of zinc. |
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