| Theme | Biocompatibility on Materials for Dialysis Equipments and Devices | |
|---|---|---|
| Title | Biocompatibility of dialyzer membranes, evaluated by influence on cutaneous microcirculation during hemodialysis | |
| Publish Date | 2004/05 | |
| Author | Motoyoshi Sato | Department of Dialysis Therapy, Social Insurance Chukyo Hospital |
| Author | Izumi Amano | Department of Dialysis Therapy, Social Insurance Chukyo Hospital |
| [ Summary ] | To clinically evaluate the biocompatibility of dialyzer membranes, we examined the action of various membranes on cutaneous microcirculation by measuring transcutaneous oxygen tension (TcPO2 during hemodialysis (HD) sessions. The pattern of TcPO2) changes during HD differed with various membranes, with a remarkable decrease in TcPO2 occurring in the early phases of HD, using a polysulfone membrane. This microcirculatory disturbance was thought to be attributable to cellular-membranes and cellular-cellular interactions during HD. In addition, this may be one factor that could contribute to the uonuniform removal of solutes. | |