| [ Summary ] |
Dialysis-related amyloidosis (DRA) has been observed in systemic organs, and is often observed in bones, joints, tendons and the peritendineum. DRA increases with the number of years of dialysis, and it is an important factor in causing degradation of quality of life for long-term dialysis patients. It is well known that (1) carpal tunnel syndrome, trigger finger and bursitis may be caused by amyloid deposition on tendons and the synovium, (2) amyloid bone cysts, pathologic fractures, destructive arthropathy from deposition on bones and joints (capsule, synovium), and (3) destructive spodyloarthropathy from deposition on the intervertebral disc periphery and intervertebral joints, occur frequently as forms of DRA locomotorium. It is necessary to pursue active surgical therapy in the early stages of these disorders so that there may be conservative, temporary treatment. Unattended, irreversable bone and joint destruction, pathological fractures, nerve and muscular alterations may follows. We describe this mainly from the viewpoint of a treatment plan. |