The Japanese Journal of Clinical Dialysis Vol.20 No.12(9)

Theme New Trends in Nutritional Assessment of Dialysis Patients
Title Dialysis dose and nutrition
Publish Date 2004/11
Author Tomohito Matsunaga Kidney Center, Eijinkai Hospital
Author Makoto Ishizaki Kidney Center, Eijinkai Hospital
[ Summary ] Chronic renal failure patients develop accelerated levels of metabolic catabolism. This means that this condition easily leads to do in malnutrition. The purpose of hemodialysis therapy is to remove uremic toxins, which are the cause of metabolic catabolism. Various indexes exist concerning dialysis dose in terms of degree of toxin reduction. Kt/V, which indicates urea reduction rates is one these indexes. However, Kt/V values depend on total body water content and, muscle mass. Therefore, Kt/V must be used of evaluations along with %CGR, LBM and the other dialysis indexes. On the other hand, the fact that underdialysis causes malnutrition, is clearly seen in a wide range of reports. These reports indicate that levels equal to or higher than those for Kt/V 1.2 are needed as minimal requirements. However, from this point, further reviews are necessary to determine whether or not increased dialysis dose are connected with improvements in nutritional condition.
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