| Theme | Characteristic Problems in Managing Female Dialysis Patients | |
|---|---|---|
| Title | Pregnancy after renal transplantation | |
| Publish Date | 2003/07 | |
| Author | Asami Takeda | Kidney Center, Nagoya 2nd Red Cross Hospital |
| Author | Kunio Morozumi | Kidney Center, Nagoya 2nd Red Cross Hospital |
| Author | Kazuharu Uchida | Kidney Center, Nagoya 2nd Red Cross Hospital |
| [ Summary ] | Fertility is usually restored in women with renal transplants, and successful pregnancies have been reported after renal transplantation. The criteria for transplant recipients contemplating pregnancy and management guidelines have been clearly outlined. Pregnancy may be considered safe at approximately 1 to 2 years after transplantation in women with good renal functions, without proteinuria, or hypertension, with no evidence of ongoing rejection and with normal allograft ultrasound result. Immunosuppressive therapy based on ciclosporin or tacrolimus, with or without steroids and azathioprine, may be continued after pregnancy. Mycophenolate mofetil and mizolibin are contra-indicated in women considering pregnancy. ACE inhibitors and angiotensin II receptor antagonists are also contra-indicated. Women of childbearing age who consider pregnancy should receive complete information and support from the transplant team. | |