| [ Summary ] |
As far as the causes of hypertension in renal failure are concerned, sodium retention is considered to be one of the most important factors. Hyperactivity of the renin-angiotensin-aldosterone system, secondary hyperparathyroidism, side effects of recombinant human erythropoietin, and an activated sympathetic nervous system are also associated causes of hypertensive renal failure. The rates of renal sclerosis have been increasing, along with an increase in the rates of atherosclerotic diseases. It was third largest cause (7.6%) for the initiation of chronic dialysis therapy in 2001 and it has been increasing yearly. Malignant renal sclerosis, which is characterized by diastolic hypertension above 130mmHg, severe retinal involvement, and rapidly progressive renal failure, must be treated properly as soon as possible. Otherwise, the prognosis for the patient will not be positive. |